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Flow cytometry analysis revealed a significant decrease in the proportion of M1 macrophages and a concurrent increase in the M2 macrophage population in the GLP-1RAs@NPs-WYRGRL group compared to both the LPS group and the NPs-WYRGRL group (Fig

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However, patients with severe fatigue usually do not respond adequately to these supplements alone, and require a more comprehensive functional approach

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Patients should never adjust or stop medication without medical guidance
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