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In fact, some patients report that stabilizing hormonal symptoms with HRT makes adhering to GLP-1 therapy easier, since mood and sleep improvements can support weight loss efforts

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Ernest Moore and colleagues hypothesized that the duodenal mucosa secretes a factor acting as a chemical excitant on the pancreas to help dispose of glucose ( [28] )

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12 Vaginal bleeding in women who do not have cancer and are not taking estrogen is often treated initially with estrogen to rule out bleeding secondary to genital atrophy