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The latter process occurs by atypical and non-vesicular secretion of adenosine triphosphate (ATP) through calcium homeostasis modulator protein 1 (CALHM1) activating afferent nerve fibers [343536]

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Mechanistically, liraglutide administration inhibited the upregulation of pain-related markers in the TNC, including calcitonin gene-related peptide (CGRP), c-fos, and components of the PI3K/Akt signaling pathway [94]

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