glp-1 receptor agonist for weight loss Balancing and muscle in GLP1 therapy GLP-1 Agonists For Obesity In
Description
GLP-1 increased the expression of the mitochondrial protective gene (PGC-1)

That is, the ADA recommends that one of these agents be considered as add-on therapy irrespective of the need for glucose lowering

My take

& Holz, G

They work by mimicking a natural gut hormone (GLP-1) that regulates glucose in a glucose-dependent manner, reducing hypoglycaemia risk

However, the authors note that the certainty of evidence was low