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This is an absolute contraindication to GLP-1 use
IECs-associated inflammasomes like NLRP6 are critical for mucosal homeostasis and infection defense (216)
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Patients who have taken these drugs have a higher risk of osteoporosis and gout, as discussed during the American Academy of Orthopaedic Surgeons annual meeting, according to NBC News
Nature 448:427434 Xie D, Li Y, Xu M, Zhao X, Chen M (2022) Effects of dulaglutide on endothelial progenitor cells and arterial elasticity in patients with type 2 diabetes mellitus
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