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FDA-approved GLP-1 medications in the United States include both daily and weekly formulations

13 Less common but important side effects include: Gallstones (rare) Kidney problems, especially in older adults who already have kidney disease Significant weight loss, which could be concerning for frail elderly people Special considerations for older adults: Stomach problems can lead to dehydration, which can be more serious in older adults

K., Moon, J

These schedules often recommend initiating treatment with a very low dose and progressively increasing it, depending on the individuals tolerance to side effects

Cureus 17(7)

the STEP 5 trial represents the most extensive study on the use of semaglutide for weight management to date