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Roughly 25 to 35 percent of the weight that GLP-1 patients lose is lean mass, according to a meta-analysis published in March

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56 The most common adverse events were gastrointestinal in the preclinical, phase1 and 2 trials similar to trials involving injectable GLP-1 agonists

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doi: 10.1016/j.cmet.2016.06.021

CRC cases comprise 59.3% colon cancer, 37.9% rectal cancer, and 2.8% anal cancer