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As a fixture in news headlines, GLP-1 drugs are a recent phenomenon

Side effects are usually mild to moderate, and in the clinical trials more than 90% of those treated with semaglutide / Wegovy and tirzepatide / Zepbound were able to stay on the medications

Systolic blood pressure reduction with tirzepatide in patients with type 2 diabetes: insights from SURPASS clinical program

As a result of popularity and support, research suggests that in the past year alone GLP-1 households doubled from being 2.3% to 4.1% of the population

Gulyaeva NV, Onufriev MV, Moiseeva YV (2021) Ischemic Stroke, Glucocorticoids, and Remote Hippocampal Damage: A Translational Outlook and Implications for Modeling

However, he acknowledged the unfortunate double stigma associated with their use, asserting that it's time to change the narrative