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The most common ones included: Nausea (17.3% of subjects) Diarrhea (11.6%) Vomiting (10.1%) Nasopharyngitis (6.2%) Dyspepsia (2.8%) Gallbladder-related events (1.6%) Acute pancreatitis (0.5%) The discontinuation rate at the highest dose was 8.5% [18]

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Po tym czasie u pacjentw leczonych retatrutidem odnotowano spadek HbA1c o 1,7-1,9 punktu procentowego, podczas gdy w grupie placebo wynosi on 0,8 punktu procentowego

Papamichou D, Panagiotakos DB, Itsiopoulos C (2019) Dietary patterns and management of type 2 diabetes: a systematic review of randomised clinical trials

Additionally, because insulin is created and released from the pancreas, inflammation of this area can cause serious health problems for those living with type 2 diabetes

The TRPV1 nociceptive ion channel is responsible not only for thermal and chemical nociception but also for inflammatory and neuropathic mechanical hyperalgesia, contributing to heightened pain sensitivity and neuroinflammation (Ma and Quirion, 2007