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Dr Johnson and colleagues noted, Further study is needed to better define the actual impact of GLP1RA on IBD-specific outcomes, ideally with more granular measures of disease activity.

As GLP-1 therapies gained approval for obesity, prescribing began to diffuse beyond endocrinology into primary care, obesity medicine, and digital health platforms

The reduction in glycated hemoglobin (HbA1c) was similar to regular human insulin

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Current recommendations suggest: 150-300 minutes of moderate-intensity aerobic exercise weekly Resistance training at least 2-3 times per week Daily movement beyond structured exercise (walking, stairs, active hobbies) Resistance training is particularly important on GLP-1 medications because up to 25-40% of weight lost can come from lean mass rather than fat

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