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The prescribing information must be included with your application

The responder rates are more decision-useful than the mean: Tirzepatide roughly doubled the odds of hitting the 25% threshold and nearly tripled them at 30%

Scientific References TripleHormone-Receptor Agonist Retatrutide for Obesity (Jastreboff et al., NEJM 2023)

Future directions Ongoing research continues to highlight the complexity of the GLP-1 system and the need for a more nuanced understanding of the distinct roles played by peripheral and central GLP-1

Some analyses, especially in more symptomatic populations, place the threshold a bit higher, closer to 1520 points for a change that patients clearly perceive as important

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