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We propose a clinical decision algorithm and highlight the need for training in gastrointestinal pharmacology, POCUS, and airway management for endoscopists

This builds muscle memory and familiarity with the sequence before the needle element enters the picture

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therefore, adopting strategies to minimize muscle and bone loss is prudent

A comprehensive literature search was performed in PubMed, Web of Science, Embase, and Scopus from inception to October 2025 using the keywords tirzepatide, GLP-1/GIP receptor agonist, obstructive sleep apnea, and obesity. Priority was given to randomized controlled trials, major observational studies, and relevant mechanistic research

Liver function, in particular, can significantly modulate rapamycins safety and efficacy