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It can also cause cardiac arrhythmias

Wang, J.Y

When total weight loss is 21%, even 26% of that coming from lean mass represents meaningful absolute numbers

Even if significant dose volume adjustments are necessary to effectively treat the new condition with a different route of administration and/or dosing, the imputed price (at parity price/unit with the first indication) may not be sufficient to realize the difference in value in the new indication due to higher disease burden, unmet need, or efficacy

PlexusDx's low starting dose and slow titration approach specifically reduces side effect intensity