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N Engl J Med 387(12):10891098 Rodriguez PJ, Goodwin Cartwright BM, Gratzl S, Brar R, Baker C, Gluckman TJ et al (2024) Semaglutide vs tirzepatide for weight loss in adults with overweight or obesity
Sinai Hospital fund for the study of gut peptides
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Key takeaways Ozempic requires gradual dose increases to minimize side effects and needs to be taken on the same day each week
However, refined experimental models are needed to fully understand the interaction between peripheral GLP-1 signalling and protein aggregation in the CNS
