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adjusted HR 1.18)

The Weibull distribution model demonstrated that upper limits of 95% CIs of were all below 1 (Table S6), consistent with an early failure profile, indicating NAEs predominantly manifest during initial treatment phases

Craft S, Cholerton B, Baker LD

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The findings are published in the journal Advances in Therapy

Switching from semaglutide to tirzepatide is one of the most common transitions when a stall persists, as the dual receptor mechanism can reignite weight loss even when single-receptor therapy has plateaued