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It solved the puzzle of GLP-1s short half-life, offering a path towards therapeutic application

12 Nov SAHPRA warns the public about GLP-1 products sold through social media platforms Pretoria, 11 November 2025 The South African Health Products Regulatory Authority (SAHPRA) cautions members of the public against purchasing or using GLP-1 (glucagon-like peptide-1) products that are being promoted and sold on various social media platforms

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In intact murine islets, blockade of N-type Ca 2+ channels with -conotoxin, but not L-type Ca 2+ channels using nifedipine, abolishes low glucose (1 mM) stimulation of glucagon secretion and blunts the GLP-1-mediated inhibitor effects