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[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Loh J.S., Mak W.Q., Tan L.K.S., Ng C.X., Chan H.H., Yeow S.H., Foo J.B., Ong Y.S., How C.W., Khaw K.Y

Obesity Disease Burden and Population Health ROI Framework Economic Cost of Obesity, Comorbidity Cascade, and GLP-1 Pharmacotherapy Value-Based Evidence Reshape Global Treatment Investment The Global Obesity Forum estimated total annual economic costs of obesity at USD 4.32 trillion annually in 2025 , representing 2.92% of global GDP and exceeding the full economic output of Germany