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Their smaller molecular structure also facilitates better tissue penetration and lower production costs, which could enhance accessibility to these novel medications

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The American diabetes association guidelines (2023) and the Chinese guidelines for the prevention and treatment of type 2 diabetes (2020) recommend that among people with type 2 diabetes who have established atherosclerotic cardiovascular disease or established kidney disease, a SGLT-2i or GLP-1RA with demonstrated cardiovascular disease benefit is recommended as part of the comprehensive cardiovascular risk reduction and/or glucose-lowering regimens

Similarly, Semaglutide is both Ozempic for diabetes and Wegovy for weight loss, and Tirzepatide is Mounjaro for diabetes and Zepbound for weight loss

Liraglutide showed resolution in 39% of treated individuals versus 9% with placebo