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Loss of muscle mass and strength not only impairs mobility and quality of life, but also worsens insulin resistance, accelerates cardiometabolic decline and increases mortality risk

Moreover, to account for possible confounders, adjusted ORs (mainly based on age, sex, body mass index [BMI], diabetes) were pooled and analyzed

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These include additional focus on social determinants of health, the healthcare system and physical activity behaviours including sleep

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This kind of correlation was not found in the case of SGLT-2 inhibitors