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Independently of these peripheral actions, GLP-1RAs show direct cerebral effects in animal stroke models, such as reduction of infarct volume, apoptosis, oxidative stress, neuroinflammation, excitotoxicity, bloodbrain barrier permeability, and increased neurogenesis, neuroplasticity, angiogenesis, and brain perfusion

Specifically, a machine-learning based attribution mapping of~68,250 posts related to GLP-1 or GLP-1/GIP agonists on the Reddit platform

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