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Both the anti-obesity and diabetes formulations have potential side effects

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What I'm confident about: Triple agonists represent a major advancement in metabolic medicine Retatrutide's Phase 2 results are genuinely impressive This medication could help people who haven't succeeded with other treatments The liver benefits are particularly exciting for people with fatty liver disease What I'm watching closely: Long-term safety data from Phase 3 trials Real-world muscle loss and how to prevent it Cost and insurance coverage Who experiences the best results vs

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The presence of diabetes accelerates the progression of MASLD

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For American adults, obesity is a tremendous problem

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Long-term expectations and maintaining results Understanding the long-term trajectory helps frame the "does it work right away" question in proper context

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10.1016/j.jacbts.2018.09.004 [DOI] [PMC free article] [PubMed] [Google Scholar] 112.Hegeds L, Moses AC, Zdravkovic M, Le Thi T, Daniels GH

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