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The remaining 486 articles were further screened according to the inclusion and exclusion criteria (Figure 1)

This time, instead of testing the drug on patients with type 2 diabetes, the drug was tested on patients without diabetes to specifically monitor their weight
The ultimate success of oral peptides or recombinant protein drugs requires a large number of clinical studies and verification by real-world patients after launch

Saxenda: This medication is approved only for weight loss
Then of course some may be metabolically healthy yet obese per BMI standards and some may be normal weight per BMI and yet metabolically obese and unhealthy
