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Description
Gut- and pancreas-derived hormone-based therapies for the treatment of cardiometabolic disease The function of GIP and GLP-1 to reduce glycemia through glucose-dependent potentiation of insulin secretion provided the initial rationale for exploring the feasibility of GLP-1R agonist (GLP-1RA)-based peptide therapies for the management of type 2 diabetes mellitus (T2DM)

The notice from the BMS suggests those using both oral HRT and GLP-1s switch to a higher dose or stronger form of progestin to preserve the protection the hormone provides against endometrial cancer

However, it is a very common secondary effect caused by dehydration from nausea, vomiting, or a decreased natural urge to drink water

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Funding This work was supported by the National Natural Science Foundation for Youths (Grant Nos
