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Marlet IR, lmestig JNE, Vilsbll T, Rungby J, Kruuse C (2018) Neuroprotective Mechanisms of Glucagon-like Peptide-1-based Therapies in Ischaemic Stroke: A Systematic Review based on Pre-Clinical Studies

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In nutrient-replete states, GLP-1induced insulin signaling suppresses adipose lipolysis, whereas during reduced caloric intake and relative glucose scarcity, lipid substrates become the dominant oxidative fuel [59, 60]

hypothesized that GLP-1R activation through exendin-4 (Ex 4) declined intrarenal RAS activity, leading to a reduction in the activity of the ATII-mediated TGF-1/Smad3 signaling pathway in mice [46]

Metabolism: ...We dont have good data on that specific question. Prosecutor: We dont have data

The evidence regarding their association with PCa remains inconclusive, prompting the authors to delve into the mechanisms through which GLP-1-RAs may influence PCa cells