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That is why 10mg/mL is the preferred concentration for researchers targeting the 12mg maintenance dose

The mechanism involves glucose-dependent insulin secretion, meaning insulin release occurs primarily when blood glucose levels are elevated, thereby reducing the risk of hypoglycemia when used as monotherapy

It does mean the risk is clinically important enough that it should not be brushed aside
This is why gradual tapering or transitioning to a maintenance dose is often easier than abrupt discontinuation

doi:10.1021/acs.jmedchem.5b00726 Loomba R, Abdelmalek MF, Armstrong MJ, et al

Their recognized neuroprotection in PD models is thought to arise from their promotion of survival of dopaminergic neurons in the SN
