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The use of GLP-1RA is a new therapeutic strategy that addresses both metabolic and cognitive/neuropsychiatric aspects, which is fundamentally important for the treatment of comorbid diseases.

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Many of the top hits are highly enriched in the enteroendocrine cells that produce incretin hormones like GLP-1 and GIP

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Tirzepatide, a novel GLP-1/GIP dual receptor agonist, shows significant advantages in glycemic management and weight control