tirzepatide glp-1 use tripled among non-diabetics, reaching $5.8B in 2022 Major physiological roles of GLP-1

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Average cost-sharing for a one-month supply of GLP-1 medications ranged from $61 to $93 in 2023

There was an increased risk of gastrointestinal disorders, hypotension, syncope, arthritic disorders, nephrolithiasis, interstitial nephritis and drug-induced pancreatitis.

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The American Society of Anesthesiologists (ASA) recommends withholding these drugs before surgery, but definitive guidelines remain unclear

Other adverse effects, including depression, sleep disturbances, and anxiety, have also been noted.While these side effects are usually transient, they can be bothersome enough to prompt some patients to discontinue treatment prematurely