semaglutide for alcohol GLP-1 Drug Substantially Reduced Heavy Consumption and Weight in Patients with Alcohol Use Disorder and Obesity A new clinical trial supported

When combined, GI side effects can be more pronounced, especially during initial titration

Chronic inflammation from Crohns disease can lead to scar tissue that thickens the intestine wall, resulting in a narrowed intestinal passage (called a stricture)

Resist the urge to swallow for as long as possible

Lifestyle interventions were the least effective treatment, the investigators found, producing a mean total body weight loss of 7.4% at the end of the treatment period, followed by a mean per-month weight regain of 0.14%, with participants reaching their pre-intervention weights within 4.1 years

Some people taking GLP-1 drugs choose to wait out the tiredness as their body adjusts

If this patient increases the dose to 15 mg (purple curve), then (a) increasing the dosing interval to 10 days reduces cost by 30% and maintains identical weight loss and (b) increasing the dosing interval to 14 days reduces cost by 50% and maintains 87% weight loss Figure 3D concerns a patient on 15 mg q1wk and shows that they can cut their costs in half and retain 79% of their weight loss