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[DOI] [PMC free article] [PubMed] [Google Scholar] Pratley R., Nauck M., Barnett A., Feinglos M., Ovalle F., Harman-Boehm I., et al

In preclinical studies, peripherally administrated GLP-1RA reaches and binds to GLP-1Rs in areas of the brain involved in the regulation of food intake in the hypothalamus and hindbrain (2)

Patients need both medical and lifestyle support

In MPTP-induced PD models, liraglutide treatment reduced the levels of neuroinflammatory markers in the substantia nigra through AMPK activation and NF-B reduction [88]

Side Effects: Most patients experience mild and temporary side effects, such as nausea or indigestion, which subside as their body adjusts

Future cost questions are also unresolved