does metformin have glp 1 GLP-1, & Rapamycin: a primer Type 2 Diabetes Medications: Metformin,

In order to better characterize the role of endogenous GLP-1 in post-prandial hypoglycemia secondary to fundoplication, the insulin response to a standardized mixed meal in affected children was measured with concomitant administration of exendin-(9-39) or vehicle through a continuous intravenous infusion

Now I found this interesting stat: roughly one in eight US adults have taken GLP-1 Drugs

Namely: No longer covering GLP-1s for weight loss : Several insurers have made the choice to stop providing coverage for these drugs when used specifically for weight loss, while still covering them for other uses like diabetes

The complex interaction of factors such as insulin resistance, glucotoxicity and lipotoxicity contribute to the pathogenesis and coexistence of diabetes and metabolic-dysfunction associated steatotic liver disease (MASLD) in a reciprocal process of exacerbating the underlying conditions [9]

but I found myself wondering if it was really all diet and exercise, or if they were also taking Wegovy / Ozempic

It is important to note that patients who fail to meet all of these risk factors (i.e., patients on stable doses without gastrointestinal symptoms) can still have delayed gastric emptying