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Adverse events and sensitivity analysis The rates of adverse events are listed in Table 3

While obesity is a chronic disease that may warrant lifelong treatment, the long-term safety, tolerability, and cost of indefinite therapy are not yet established [26, 27]
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What felt like a normal meal before tirzepatide might now cause hours of uncomfortable fullness

At the individual level, tailored goals, dietary and weight self-monitoring, and structured problem-solvingsupported by digital tools such as apps or wearablescan enhance adherence and patient engagement

Christine Albert is currently President of Heart Rhythm Society
