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The CCI, developed to predict long-term mortality, has been adapted for use with various data sources, including ICD-9 and ICD-10 codes, and is known for its reliability and validity in diverse clinical populations

In patients with T2D at high CV risk in PIONEER 6, oral semaglutide reduced HbA 1c compared with placebo as an add-on to standard of care (mean change of 1.0% vs 0.3%) at the end of the trial (not statistically analyzed

Ghrelin is famously known as the hunger hormone

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Alabduljabbar K, Al-Najim W, le Roux CW (2022) The Impact Once-Weekly Semaglutide 2.4 mg Will Have on Clinical Practice: A Focus on the STEP Trials Nutrients