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We know that the more weight loss achieved with a GLP-1 often results in more blood pressure reduction, says Laffin

Mid-dose tirzepatide users (7.5 to 10mg) should plan for 25 to 30 days

semaglutide generally needs no dose adjustment Patients with kidney disease : Generally no dose adjustments needed for either medication, but monitoring is advised People with diabetes : Should be aware of the risk of diabetic retinopathy progression with rapid improvement in blood glucose control

Ryu S, Chang Y, Kim YS, et al

2.4.4 Sensitivity analysis A series of sensitivity analyses were performed to assess the robustness of the results

Several factors compound the indirect pathways described above, creating significantly higher vulnerability in certain populations