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Interestingly, the pattern of fat reduction wasnt uniform across different adipose depots
In a 2-year trial involving patients with type 2 diabetes mellitus (T2DM) and high cardiovascular risk, more events of diabetic retinopathy complications occurred in patients treated with semaglutide 0.5 and 1 mg once weekly injections (3%) compared to placebo (1.8%)

The lack of dedicated research on this topic underscores the need for further investigation, especially given the increasing use of semaglutide for diabetes management and weight loss

F.et al (2006)

These results are why insurers are increasingly adding GLP-1 coverage for weight loss, though eligibility criteria remain strict

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