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Moreover, 1 recent study assessed the presence of peripherally injected semaglutide in the NAc of male and female rats and found the GLP-1 analog in the NAc of both males and females (141)

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Participants in the semaglutide group achieved a weight loss of at least 5%, 10%, or 15%, and improvements in secondary endpoints, such as waist circumference, blood pressure, and lipid levels, compared to the placebo group

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