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Reductions in 3-point major adverse CV events (3P-MACE) and CV death have been noted in some of these CVOTs, with additional benefits including reduced risks of hospitalisation for heart failure, progression of renal disease, and all-cause mortality

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How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the heart failure association (HFA) of the European society of cardiology (ESC)

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Search items included medication-related itemsGLP-1 receptor agonist, GLP-1RA, dual-agonist, and glucagon-like peptide-1 along with cardiovascular outcome-related items major adverse cardiovascular event, myocardial infarction, coronary artery disease, peripheral arterial disease, heart failure, hypertension, and atrial fibrillation. Studies were meticulously screened and included if they reported cardiovascular outcomes related to MACE, myocardial infarction (MI), CAD, PAD, HF, hypertension (HTN), or AF

The recent cuts to federal labs and university-based research programs may change this going forward