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While it can be unpleasant, diarrhea often lessens as the body becomes accustomed to the medication over time

Jump to: What the TRIUMPH-1 trial found | How retatrutide works | How it compares to Mounjaro and Wegovy | When could retatrutide be available in the UK

Well that brings us onto the final piece of the discovery arc the trial that compares the drug classes against each other for the first time

In addition to acting on GLP-1 receptors, tirzepatide also targets GIP receptors located in the pancreas, adipose (fat) tissue, and brain regions involved in eating behavior and insulin regulation

Let's find out where these annoyances come from and how to deal with them

Your prescriber will outline the titration schedule usually starting at 0.25mg/week for the first 4 weeks before escalating