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The pharmacokinetics of semaglutide across multiple trials offer a surprisingly clean window into how this molecule and this biology actually works.

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Up to date, DS seems to be a rare long-term complication after OAGB and revisional/conversional interventions might not be needed

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But once that pharmacological scaffolding is gone, the old dynamics often roar backstronger than before.

Keep an open mind, but not so open that your brains fall out. Richard P