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[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Solomon S.D., McMurray J.J.V., Claggett B., de Boer R.A., DeMets D., Hernandez A.F., Inzucchi S.E., Kosiborod M.N., Lam C.S.P., Martinez F., et al

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However, caution is recommended in the use of SGLT2i in people with a high risk of amputation or skin ulcers in the lower extremities [89]

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This effect is mostly related to the dose, with higher doses generally creating more appetite suppression and weight loss

Clinical data shows that Exenatidea common GLP-1RAhas been associated with systemic allergic reactions, which emphasizes the need for meticulous patient selection and monitoring