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2025;27(Suppl 2):6688

Gastrointestinal side effects, including nausea, vomiting, diarrhea, and constipation, are common but typically mild to moderate and often decrease over time (Wilding et al., 2021)

After a phase 2b clinical trial in patients with biopsy-proven NASH without cirrhosis (FLINT trial) in which OCA displayed a beneficial impact on fibrosis without resolution of advanced fibrosis and at least of 2 points improvement in NASH compared to placebo [51], this drug is now being tested in a large phase 3 randomized, placebo-controlled trial (REGENERATE trial, NCT2548351) to evaluate the long-term effects on NASH and fibrosis in patients with stage 13 fibrosis

Never discontinue Ozempic without medical guidance, except in cases of suspected severe allergic reaction, as stopping treatment may compromise your diabetes control and overall health