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Before any peptide is mixed with bacteriostatic water, researchers need to know how much water to add to achieve the desired concentration, how many research units each syringe increment will deliver, and how many research units a full vial will yield

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Participants received diet (500kcaldeficit per day) and exercise counseling during 2-week run-in, before being randomly assigned (with a telephone or web-based system) to once-daily subcutaneous liraglutide (1.2, 1.8, 2.4 or 3.0mg, n=9095), placebo (n=98) or open-label orlistat (120mg 3, n=95)