glp 1 drugs contraindications GLP-1 Medications: Everything You Need to Know GI Adverse Effects of Glucagon-Like
Description
Decreased aging, improved performance that are attributable to improved blood pressure control, improved glycemic control, weight loss, increased renal blood flow, restoration of normal glomerular hemodynamics, enhanced autoregulation, and prevention of oxidative injury are potential contributors to reducing cardiovascular events through the kidney-cardiovascular axis [85]
They also support weight loss and reduce cardiovascular risk
SGLT2i were significantly less effective in reducing HbA 1c than GLP-1RA, suggesting that protection against eGFR decline may not directly rely on glycaemic control
HbA1c reduction 4.1.1
More concerning but less common side effects include gallbladder problems , potential thyroid issues (a black box warning exists for medullary thyroid carcinoma risk in animal studies), and hair loss related to rapid weight loss rather than the medication itself
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