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How to Poop Better if Youre on a GLP-1 Medication Glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound) carry a few well-known side effects, but theres one that often goes overlooked: constipation

Rapidly pushing past about 40 to 50g a day is a common trigger for bloating and discomfort

doi:10.1097/og9.0000000000000077 Drummond RF, Seif KE, Reece EA

Medical supervision is crucial when using Ozempic, as patients may lose not only fat but also essential muscle mass if not monitored properly

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