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The researchers compared the one-year risk of HF hospitalization or death in new users of each GLP-1 drug to the risk of those outcomes in a placebo group of patients taking sitagliptin, a diabetes drug known to have no impact on HFpEF

17 Periods of protection from patents and exclusivities overlap, and both can block the FDA from approving generic versions of brand-name products

The institute recommended that existing GLP-1 makers, and those with products in the pipeline, should consider steep discounts to prices in exchange for higher volume. What has to happen is we have to move from a low-volume, high-price business model, to a high-volume, low-price business model, Nunn said

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( 10.1056/NEJMoa1603827) [DOI] [PMC free article] [PubMed] [Google Scholar] 109.Holman RR, Bethel MA, Mentz RJ, Thompson VP, Lokhnygina Y, Buse JB, Chan JC, Choi J, Gustavson SM, Iqbal Net al