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B12 supplementation addresses a common deficiency seen in both ketogenic dieters and GLP-1 users

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Results at 48 weeks, highest dose (12 mg): Mean weight loss: 24.2% of body weight Percentage achieving 15% weight loss: 83% Percentage achieving 25% weight loss: 26% For comparison, tirzepatide 15 mg in SURMOUNT-1 produced 22.5% mean weight loss at 72 weeks a slightly longer treatment duration, in a slightly different population, making direct comparison imprecise but directionally informative

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Limit Greasy or Highly Processed Foods These can worsen side effects like nausea, bloating, or reflux