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Adenosine triphosphate is co-secreted with glucagon-like peptide-1 to modulate intestinal enterocytes and afferent neurons

Other clinically relevant GI complications include cholelithiasis, which occurred about 50 % more often, and gastroesophageal reflux disease (GERD), which occurred roughly twice as often, in patients receiving GLP-1 therapies compared with placebo [33]

increasing the size of this group and shifting the amide from the to the position resulted in a loss of inhibitory activity

Red Persistent vomiting, inability to keep fluids down, dehydration, severe abdominal pain, major weakness, falls, or a meaningful decline in daily function

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Glucagon-Like Peptide-1 Receptor ), and other class B GPCRs (Hollenstein et al., 2014)