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Other symptoms of the disease also influence Rett syndrome sleep patterns: Digestive and mood issues: Gastro-esophageal reflux disease (GERD) or anxiety can make it much harder to stay asleep through the night

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Semaglutide did not slow progression on the Clinical Dementia Rating Sum of Boxes, although it did improve Alzheimer's-related biomarkers (Novo Nordisk, 2025)

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