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"The novel glucagonagonist component introduces lessunderstood longterm safety considerations, so it is imperative that patients are followed closely by healthcare professionals experienced with this class of medicines, with cautious, stepwise use, despite the impressive efficacy," he cautioned.

In women, excess weight can interfere with ovulation, menstrual cycles and egg quality, while in men it may contribute to lower testosterone levels and reduced sperm quality

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Its important to be mindful of their relationship with food, and since GLP-1s suppress appetite, this can make social occasions more difficult to navigate

Users who expected rapid changes in weight or appetite were often disappointed