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But when a medication is taken orally, it has to survive the harsh, acidic environment of the stomach and then pass through the liver, a process called the 'first-pass effect,' which can significantly break down the drug before it ever reaches your bloodstream

The medication should be inspected for clarity and any discoloration or particles before use, administered weekly without regard to meals, and injected subcutaneously into the abdomen, thigh, or upper arm, ensuring the injection site is rotated with each dose

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You may qualify for bariatric surgery on the NHS if you meet strict criteria - usually a BMI of 40 or higher , or 35 to 40 if you have a serious weight-related condition such as type 2 diabetes or high blood pressure

It sounds a cautionary note for short-term use without a more comprehensive approach to long-term weight management, and highlights the importance of primary prevention. Previous studies have suggested weight loss medication can also have a beneficial impact on other areas of a patients health, as seen in the study into drugs that could halve heart patients risk of an early death