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Maguire, J
Some patients choose to restart semaglutide after a break, which may require going through the prior authorization process again
Direct cortisol-lowering is not semaglutide's primary mechanism, but clinical observations suggest GLP-1 activation may normalize cortisol's diurnal rhythm and reduce stress-induced cortisol spikes
Many users report losing 1 to 2 pounds per week during this phase
Rotating sites weekly protects skin health
Monitor ECG & K levels frequently
